|Document ID (ISN)||105879|
|Convention or series no.
||ECETOC JACC No.49
||Vinylidene fluoride (CAS No. 75-38-7)
||European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC), Avenue E. Van Nieuwenhuyse 4, Bte. 6, 1160 Bruxelles, Belgium, Nov. 2005. 54p. Illus. 81 ref.
||Conclusions of this criteria document on vinylidene fluoride (VDF): VDF has low acute and chronic toxicity in laboratory animals. It is not genotoxic either in vitro or in vivo. Although rats developed carcinomas in a one-year oral study, subsequent lifetime inhalation studies in rats and mice showed no adverse effects at high doses. It is therefore unlikely that VDF has significant long-term toxic or carcinogenic properties. VDF has no effects on rat fertility or reproduction. A teratology study did not indicate any embryotoxic, foetotoxic or teratogenic effects at high concentrations. There are no data on the effects of human exposure. The ACGIH has established a threshold limit value of 500ppm or 1300mg/m3.
||threshold limit values; acute toxicity; criteria document; chronic toxicity; animal experiments
||B - Chemical safety information sheets
|Country / State or Province||Belgium|
||Toxic and dangerous substances
|Broad subject area(s)