|Document ID (ISN)||105843|
|ISSN - Serial title
||0091-6765 - Environmental Health Perspectives
|Convention or series no.
||Chia S.E., Zhou H., Tham M.T., Yap E., Dong N.V., Hong Tu N.T., Chia K.S.
||Possible influence of δ-aminolevulinic acid dehydratase polymorphism and susceptibility to renal toxicity of lead: A study of a Vietnamese population
||Oct. 2005, Vol.113, No.10, p.1313-1317. Illus. 33 ref.
||In a cross-sectional study of 276 lead-exposed workers in Vietnam, all workers were measured for blood lead levels and for various urinary markers of renal toxicity. Six newly identified polymorphisms located on the ALAD (δ-aminolevulinic acid dehydratase) gene were examined to determine whether they could modify the relationship between blood lead and some renal parameters. It was found that one polymorphism was able to modify the association of blood lead concentrations with certain renal parameters. Further studies are needed to confirm this observation.
||lead; individual susceptibility; renal function tests; renal diseases
||Viet Nam; determination in urine; determination in blood
||D - Periodical articles
|Country / State or Province||Singapore; Viet Nam|
Toxic and dangerous substances
|Broad subject area(s)
Occupational medicine, epidemiology
Diseases of the kidney and the urinary system
Lead and compounds