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Document ID (ISN)105765
CIS number 06-1343
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2006
Convention or series no.
Author(s) Winker R., Rüdiger H.W.
Title Reproductive toxicology in occupational settings: An update
Bibliographic information Jan. 2006, Vol.79, No.1, p.1-10. Illus. 98 ref.
Internet access http://www.springerlink.com/content/t5qm6h40818q5q28/fulltext.pdf [in English]
Abstract The aim of this literature review was to study the relationship between occupational exposures and fertility, developmental effects and genetic changes that lead to genetic malformations or to genetic disease. It aimed in particular to assess whether occupational exposures are responsible for 15% involuntarily childless couples, 10-20% spontaneous abortions and 3% birth defects. The review identified some substances and occupational settings that may affect fertility function, but no reliable evidence was found for developmental effects of work conditions. The decreasing fertility of women in Western countries can be better explained by the increasing female reproduction age rather than by occupational exposures. Also, the rates for spontaneous abortions and birth defects cannot be explained by industrial exposures at the workplace.
Descriptors (primary) antifertility effects; harmful substances; expectant mothers; risk factors; teratogenic effects
Descriptors (secondary) literature survey; threshold limit values; 2-bromopropane; genetic abnormalities; manganese and compounds; hot workplaces; mercury and compounds; carbon disulfide; lead and compounds; Nemagon; abortion; Germany
Document type D - Periodical articles
Country / State or ProvinceAustralia
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Toxicology