| Document ID (ISN) | 105603 |
| CIS number |
06-1098 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2005 |
| Convention or series no. |
|
| Author(s) |
Li A.A., Mink P.J., McIntosh L.J., Teta M.J., Finley B. |
| Title |
Evaluation of epidemiologic and animal data associating pesticides with Parkinson's disease |
| Bibliographic information |
Oct. 2005, Vol.47, No.10, p.1059-1087. Illus. 147 ref. |
| Abstract |
To evaluate the evidence regarding the association between Parkinson's disease (PD) and exposure to pesticides, this study examined both epidemiologic studies and animal studies for PD-like effects following systemic pesticide exposure. The findings of the epidemiologic studies were found to be mixed and without consistent exposure-response or pesticide-specific patterns. These studies were furthermore limited by a lack of detailed and validated pesticide exposure assessment. In animal studies, no pesticide has yet demonstrated the selective set of clinical and pathologic signs that characterize human PD, particularly at levels relevant to human populations. It is concluded that the animal and epidemiologic data reviewed do not provide sufficient evidence to support an association between pesticide exposure and PD. |
| Descriptors (primary) |
pesticides; Parkinson's disease |
| Descriptors (secondary) |
literature survey; paraquat; animal experiments; epidemiologic study; exposure evaluation |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Occupational pathology
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
Occupational medicine, epidemiology
|
| Browse category(ies) |
Diseases of the nervous system
Agricultural chemicals
|
