|Document ID (ISN)||105492|
|ISSN - Serial title
||1077-3525 - International Journal of Occupational and Environmental Health
|Convention or series no.
||Huh J.W., Hong S.B., Lim C.M., Do K.H., Lee J.S., Koh Y.S.
||Sequential radiologic and functional pulmonary changes in patients with paraquat intoxication
||July-Sep. 2006, Vol.12, No.3, p.203-208. Illus. 24 ref.
||http://www.ijoeh.com/pfds/IJOEH_1203_Huh.pdf [in English]
||The sequential changes of paraquat-induced pulmonary damage were studied using high-resolution computed tomography (HRCT) and pulmonary function tests (PFTs) in long-term follow-up. Among the cohort of 27 patients who had ingested paraquat, the HRCT findings showed a normal (n=14) and an abnormal group (n=13). Increased paraquat ingestion in the abnormal group was associated with more rapid and severe pulmonary changes. Ground-glass opacity on HRCT peaked on day 7 after ingestion. Between 2 weeks and 1 month, consolidation increased and pulmonary fibrosis progressed, and slow improvements were observed for up to six months. Compared with the PFT results obtained at 1 and 6.5 months, FVC, FEV1, and diffusing capacity all improved slightly. Lung changes after paraquat intoxication are functionally and radiologically reversible following treatment. [Abstract supplied by the journal]
||poisoning; radiological changes; pulmonary function; paraquat
||ingestion; tomography; pulmonary fibrosis
||D - Periodical articles
|Country / State or Province||Korea, Republic of|
||Toxic and dangerous substances
|Broad subject area(s)