|Document ID (ISN)||105443|
|ISSN - Serial title
||0355-3140 - Scandinavian Journal of Work, Environment and Health
|Convention or series no.
||Bardin J.A., Gore R.J., Wegman D.H., Kriebel D., Woskie S.R., Eisen E.A.
||Registry-based case-control studies of liver cancer and cancers of the biliary tract nested in a cohort of autoworkers exposed to metalworking fluids
||June 2005, Vol.31, No.3, p.205-211. 34 ref.
||This study on hepatobiliary cancer (liver and biliary tract) was conducted in the form of a registry-based case-control study nested in a cohort of workers from three automobile manufacturing plants with potential exposure to metalworking fluids. 63 cases of hepatobiliary cancer were identified from the cohort by the Michigan cancer registries. Each case was matched to 10 controls. Odds ratios were estimated in conditional logistic regression models for lifetime exposure to straight mineral oils, and to soluble and synthetic metalworking fluids and fluid components. Overall, hepatobiliary cancer was not associated with exposure to metalworking fluids. However, there is limited evidence that exposure to straight metalworking fluids is associated with biliary tract cancer. Findings need to be examined further in other exposed populations.
||biliary tract diseases; motor vehicle industry; liver cancer; cutting fluids
||USA; cohort study; case-control study; mineral oils
||D - Periodical articles
|Country / State or Province||USA|
||Metal production and metalworking
Toxic and dangerous substances
|Broad subject area(s)
Occupational medicine, epidemiology
||Motor vehicle manufacturing industry