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Document ID (ISN)105443
CIS number 06-904
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 2005
Convention or series no.
Author(s) Bardin J.A., Gore R.J., Wegman D.H., Kriebel D., Woskie S.R., Eisen E.A.
Title Registry-based case-control studies of liver cancer and cancers of the biliary tract nested in a cohort of autoworkers exposed to metalworking fluids
Bibliographic information June 2005, Vol.31, No.3, p.205-211. 34 ref.
Abstract This study on hepatobiliary cancer (liver and biliary tract) was conducted in the form of a registry-based case-control study nested in a cohort of workers from three automobile manufacturing plants with potential exposure to metalworking fluids. 63 cases of hepatobiliary cancer were identified from the cohort by the Michigan cancer registries. Each case was matched to 10 controls. Odds ratios were estimated in conditional logistic regression models for lifetime exposure to straight mineral oils, and to soluble and synthetic metalworking fluids and fluid components. Overall, hepatobiliary cancer was not associated with exposure to metalworking fluids. However, there is limited evidence that exposure to straight metalworking fluids is associated with biliary tract cancer. Findings need to be examined further in other exposed populations.
Descriptors (primary) biliary tract diseases; motor vehicle industry; liver cancer; cutting fluids
Descriptors (secondary) USA; cohort study; case-control study; mineral oils
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Metal production and metalworking
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Gastrointestinal diseases
Motor vehicle manufacturing industry