|Document ID (ISN)||105106|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Suarthana E., Vergouwe Y., Nieuwenhuijsen M., Heederik D., Grobbee D.E., Meijer E.
||Diagnostic model for sensitization in workers exposed to occupational high molecular weight allergens
||Sep. 2005, Vol.48, No.3, p.168-174. Illus. 16 ref.
||Occupational allergy is frequent among workers exposed to high molecular weight allergens. The aim of this study was to develop and validate a generic diagnostic model for identifying workers at high risk of being sensitized to these allergens. The model was developed using data from Dutch laboratory animal workers and bakers using logistic regression analysis. The model takes into account working hours per week, work-related symptoms, total IgE and IgE to common allergens. Significant interactions between the type of work and the predictors resulted in different scores for animal workers and bakers. Internal and external validation showed that the model was satisfactorily calibrated and discriminated between workers at high and low risk of being sensitized.
||bakery products industry; allergens; sensitization; experimental animals; diagnosis; laboratory work
||immunoglobulins; autoimmunization; Netherlands
||D - Periodical articles
|Country / State or Province||United Kingdom; Indonesia; Netherlands|
||Toxic and dangerous substances
|Broad subject area(s)