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Document ID (ISN)105101
CIS number 06-644
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2005
Convention or series no.
Author(s) Chen S.S., Chen T.J., Lin C.H., Tseng Y.T., Lai S.L.
Title Neurobehavioral changes in Taiwanese lead-exposed workers
Bibliographic information Sep. 2005, Vol.47, No.9, p.902-908. 53 ref.
Abstract Dysfunction of the central nervous system (CNS) was evaluated among male workers who had been exposed to lead for at least three years and who had elevated blood lead levels (BLLs). According to their current BLLs, 33 and 28 subjects were assigned to the medium (40-80µg/dL) and low (<40µg/dL) BLL groups, respectively. Sixty-two non-exposed healthy men served as the control group. A computerized evaluation system found significantly impaired neurobehavioral functions in the medium BLL group, including slow performance of psychomotor tasks, impaired processing of visual-spatial information, reduced memory and learning functions, low performance accuracy, slow execution of responses, and poor attentional control. Subtle CNS dysfunction is therefore possible among lead-exposed workers having no obvious neurological and cognitive deficits.
Descriptors (primary) central nervous system; neurological effects; lead and compounds; Taiwan (China)
Descriptors (secondary) cognitive performance; lead; disturbances of memory; perceptual-motor performance; determination in blood; case-control study; neuropsychic effects; dose-response relationship; concentration ability
Document type D - Periodical articles
Country / State or ProvinceTaiwan (China)
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the nervous system
Lead and compounds
Inorganic substances