| Document ID (ISN) | 105007 |
| CIS number |
06-612 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
2005 |
| Convention or series no. |
|
| Author(s) |
Sennbro C.J., Littorin M., Tinnerberg H., Jönsson B.A.G. |
| Title |
Upper reference limits for biomarkers of exposure to aromatic diisocyanates |
| Bibliographic information |
Aug. 2005, Vol.78, No.7, p.541-546. Illus. 28 ref. |
| Abstract |
The objectives of this study were to determine the levels of biomarkers of exposure to several diisocyanates in the urine and blood of occupationally unexposed workers and to calculate their upper reference limits (URLs). Biomarker levels were determined in urinary and plasma samples obtained from 121 occupationally unexposed workers. URLs were then calculated based on these biomarker levels and the levels in an occupationally exposed group of workers. These URLs may be used for screening for occupational exposure, a worker with a biomarker level above the URL being classified as occupationally exposed. Biomarkers of aromatic diisocyanates, especially biomarkers of 4,4'-methylenediphenyl diisocyanate, were present among occupationally unexposed workers, but the source and nature of the exposure is unknown. |
| Descriptors (primary) |
exposure tests; isocyanates |
| Descriptors (secondary) |
diphenylmethane diisocyanate; naphthylene diisocyanate; 2,6-tolylene diisocyanate; determination in urine; determination in blood; description of technique; 2,4-tolylene diisocyanate |
| Document type |
D - Periodical articles |
| Country / State or Province | Sweden |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Biological monitoring
Isocyanates
Cyano compounds
|
