|Document ID (ISN)||104864|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Jarvis J., Seed M.J., Elton R.A., Sawyer L., Agius R.M.
||Relationship between chemical structure and the occupational asthma hazard of low molecular weight organic compounds
||Apr. 2005, Vol.62, No.4, p.243-250. Illus. 31 ref.
||06-0372.pdf [in English]
||The aim of this literature survey was to investigate relationships between chemical structure and reported occupational asthma for low molecular weight organic compounds. Nitrogen- or oxygen-containing functional groups such as isocyanates, amines, acid anhydrides and carbonyls were associated with occupational asthma, particularly when the functional group was present twice or more in the same molecule. Results suggest that chemical cross-linking is an important molecular mechanism leading to the development of occupational asthma.
||molecular structure; asthma; organic compounds
||literature survey; carbonyls; statistical evaluation; amines; isocyanates; carboxylic acid anhydrides
||D - Periodical articles
|Country / State or Province||United Kingdom|
Toxic and dangerous substances
|Broad subject area(s)
Occupational medicine, epidemiology
||Diseases of the respiratory system (except for pneumoconiosis & similar)