|Document ID (ISN)||104856|
|ISSN - Serial title
||0340-0131 - International Archives of Occupational and Environmental Health
|Convention or series no.
||Uitti J., Nordman H., Halmepuro L., Savolainen J.
||IgG4 response to fur animal allergens among fur workers
||Feb. 2005, Vol.78, No.1, p.71-74. 18 ref.
||The aim of this study was to determine whether IgG4 antibodies to allergens in urine extracts from fur animals were associated with positive prick tests to the same allergens and with the occurrence of respiratory symptoms among fur workers. IgG4 antibodies to mink and silver fox urine were analysed in fur farmers and three referent groups from the plastics industry. The fur workers had higher IgG4 values than other groups and also had urinary IgG4 antibodies more frequently than the other groups. Among the exposed subjects, IgG4 antibodies correlated with positive skin prick tests to the same allergens and were associated with symptoms among the exposed workers. Results indicate that IgG4 antibodies are a good indicator of exposure to these allergens in fur workers.
||allergens; fur industry; handling of animals; immunology
||rhinitis; eye irritation; antibodies; frequency rates; case-control study; skin tests; symptoms
||D - Periodical articles
|Country / State or Province||Finland|
||Toxic and dangerous substances
|Broad subject area(s)
||Footwear, leather and fur industry