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Document ID (ISN)104855
CIS number 06-367
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2005
Convention or series no.
Author(s) Bilban M., Bilban Jakopin C., Ogrinc D.
Title Cytogenic tests performed on operating room personnel (the use of anaesthetic gases)
Bibliographic information Feb. 2005, Vol.78, No.1, p.60-64. 23 ref.
Abstract The cytogenic effects of chronic exposure to small doses of anaesthetic gases was studied in a group of workers handling these gases in operating theatres. Results were compared with those from radiologists exposed to ionizing radiation and from a group of Slovene citizens who were never exposed to genotoxic agents. Tests included structural chromosomal aberrations (SCA), sister chromatid exchanges (SCE) and the micronucleus assay (MN). The average frequency of SCAs in the study group was significantly higher than in the group of radiologists and Slovene citizens. The frequency of SCE and MN was also significant. These findings confirm those of previous studies, indicating that exposure to anaesthetic gases induces changes in human chromosomes.
Descriptors (primary) inhalation anaesthetics; genetic effects; exposure evaluation; operating theatres
Descriptors (secondary) Slovenia; case-control study; determination in air; chromosome changes; risk factors; hospitals
Document type D - Periodical articles
Country / State or ProvinceSlovenia
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Exposure evaluation