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Document ID (ISN)104650
CIS number 06-131
ISSN - Serial title 1231-868X - Podstawy i Metody Oceny Środowiska Pracy
Year 2005
Convention or series no.
Author(s) Starek A.
Title (2-Methoxymethylethoxy)propanol: Documentation of maximum admissible values for occupational exposure
Original title (2-Metoksymetyloetoksy)-propanol: Dokumentacja proponowanych wartości dopuszczalnych wielkości narażenia zawodowego [in Polish]
Bibliographic information 2005, Vol.43, No.1, p.91-101. 16 ref.
Abstract (2-Methoxymethylethoxy)-propanol (dipropylene glycol methyl ether, DGME) is a colourless liquid with low vapour pressure, an ethereal odour and bitter taste. It has relatively low toxicity in humans and laboratory animals. Irritation of the eyes and respiratory tract as well as depression of the central nervous system are recognised as critical effects. No embryotoxic, foetotoxic or teratogenic effects have been found in toxicological studies. On the basis of the no-observed-adverse-effect-level (NOAEL) for irritation obtained from experiments on rats and the appropriate uncertainty factor, the maximum admissible concentration was set at 240 mg/m3. A short-term exposure limit of 480 mg/m3 and irritant (I) notation are recommended.
Descriptors (primary) toxic effects; toxicology; dipropylene glycol methyl ether; threshold limit values
Descriptors (secondary) neurotoxic effects; eye irritation; Poland; irritants
Document type D - Periodical articles
Country / State or ProvincePoland
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Occupational exposure limits
Glycol ethers