| Document ID (ISN) | 104617 |
| CIS number |
06-201 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2004 |
| Convention or series no. |
|
| Author(s) |
Magnusson L.L., Bonde J.P., Olsen J., Möller L., Bingefors K., Wennborg H. |
| Title |
Paternal laboratory work and congenital malformations |
| Bibliographic information |
Aug. 2004, Vol.46, No.8, p.761-767. Illus. 43 ref. |
| Abstract |
A study was carried out on male employees of biological and biomedical institutions in Swedish universities from 1970 to 1989. A control group comprised workers in non-biological departments of the same universities. Female partners were linked to the Swedish Medical Birth register. The total number of pregnancies available for study was 4170. The relationship between major malformations and exposure to laboratory work and to specific laboratory agents or techniques before the third trimester of pregnancy was analysed using logistic regression. There were a total of 81 births with at least one major malformation: 44 among those exposed to paternal laboratory work and 37 among the reference group. It was concluded that while the prevalence of congenital malformations was not increased in the offspring of male laboratory workers in general, paternal work with agents such as carcinogens could be of concern. |
| Descriptors (primary) |
carcinogens; male workers; teratogenic effects; laboratory work; parental exposure |
| Descriptors (secondary) |
Sweden; epidemiologic study; organic solvents; radioactive substances |
| Document type |
D - Periodical articles |
| Country / State or Province | Denmark; Sweden |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Biological hazards
|
| Browse category(ies) |
Genetic factors in reaction to exposures
Antifertility and prenatal effects
|
