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Document ID (ISN)104596
CIS number 06-113
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2003
Convention or series no.
Author(s) Luo J.C.J., Chang H.Y., Chang S.J., Chou T.C., Chen C.J., Shih T.S., Huang C.C.
Title Elevated triglyceride and decreased high density lipoprotein level in carbon disulfide workers in Taiwan
Bibliographic information Jan. 2003, Vol.45, No.1, p.73-78. 31 ref.
Abstract The aims of this study were to examine the dose-response relationship of carbon disulfide (CS2) exposure and triglyceride and lipoprotein levels in 132 exposed workers recruited from two viscose rayon plants. Air sampling was performed to determine the CS2 exposure of workers. Demographic data and work history were gathered by self-administered questionnaires. Lipid profile tests were performed by routine methods. The average CS2 exposure concentration was 50.6▒25.6ppm in the high-exposure group, 12.9▒5ppm in the mid-exposure group, and 3.5▒1.2ppm in the low-exposure group. In the high, medium and low exposure groups, elevated triglyceride levels were found in 21 out of 33 workers, 27 out of 64 workers and 14 out of 35 workers, respectively. There was a lower prevalence of elevated high-density lipoprotein cholesterol (HDL) level in high CS2 exposure workers versus low-exposure workers (15.2% vs. 31.4%). This study suggests that elevated triglyceride level and decreased HDL level are associated with CS2 exposure. The study also suggests that exposure to CS2 concentrations of above 23.2ppm are significantly associated with increased risk of coronary heart disease.
Descriptors (primary) viscose rayon industry; lipoproteins; carbon disulfide
Descriptors (secondary) exposure evaluation; dose-response relationship; frequency rates; determination in blood; determination in air
Document type D - Periodical articles
Country / State or ProvinceTaiwan (China)
Subject(s) Chemicals, plastics and rubber
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic sulfur compounds
Inorganic substances