|Document ID (ISN)||104592|
|ISSN - Serial title
||1076-2752 - Journal of Occupational and Environmental Medicine
|Convention or series no.
||Śliwińska-Kowalska M., Zamyslowska-Szmytke E., Szymczak W., Kotylo P., Fiszer M., Wesolowski W., Pawlaczyk-Luszczynska M.
||Ototoxic effects of occupational exposure to styrene and co-exposure to styrene and noise
||Jan. 2003, Vol.45, No.1, p.15-24. Illus. 17 ref.
||The effects on hearing of occupational exposure to styrene and of combined exposures to styrene and noise were evaluated in 290 yacht yard and plastics factory workers and in a control group of unexposed and noise-exposed workers. Subjects were assessed by means of a detailed questionnaire and audiometric examinations. There was an almost four-fold increase in the odds of developing hearing loss from styrene exposure. In cases of the combined exposures to styrene and noise, the odds ratios were two to three times higher than the respective values for styrene-only and noise-only exposed subjects. The mean hearing thresholds were significantly higher in the solvent-exposed group than in the unexposed reference group at all frequencies tested. The study provides evidence that occupational exposure to styrene is related to an increased risk of hearing loss. Combined exposures to noise and styrene seem to be more ototoxic than exposure to noise alone.
||noise; styrene; ototoxic effects; hearing loss; plastics converting industry; shipyards
||organic solvents; case-control study; audiometric tests; synergism; dose-response relationship; hearing threshold
||D - Periodical articles
|Country / State or Province||Poland|
||Toxic and dangerous substances
Noise, hearing and vibration
|Broad subject area(s)
||Diseases of the ear and hearing damage
Shipbuliding and ship repair