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Document ID (ISN)104592
CIS number 06-96
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2003
Convention or series no.
Author(s) Śliwińska-Kowalska M., Zamyslowska-Szmytke E., Szymczak W., Kotylo P., Fiszer M., Wesolowski W., Pawlaczyk-Luszczynska M.
Title Ototoxic effects of occupational exposure to styrene and co-exposure to styrene and noise
Bibliographic information Jan. 2003, Vol.45, No.1, p.15-24. Illus. 17 ref.
Abstract The effects on hearing of occupational exposure to styrene and of combined exposures to styrene and noise were evaluated in 290 yacht yard and plastics factory workers and in a control group of unexposed and noise-exposed workers. Subjects were assessed by means of a detailed questionnaire and audiometric examinations. There was an almost four-fold increase in the odds of developing hearing loss from styrene exposure. In cases of the combined exposures to styrene and noise, the odds ratios were two to three times higher than the respective values for styrene-only and noise-only exposed subjects. The mean hearing thresholds were significantly higher in the solvent-exposed group than in the unexposed reference group at all frequencies tested. The study provides evidence that occupational exposure to styrene is related to an increased risk of hearing loss. Combined exposures to noise and styrene seem to be more ototoxic than exposure to noise alone.
Descriptors (primary) noise; styrene; ototoxic effects; hearing loss; plastics converting industry; shipyards
Descriptors (secondary) organic solvents; case-control study; audiometric tests; synergism; dose-response relationship; hearing threshold
Document type D - Periodical articles
Country / State or ProvincePoland
Subject(s) Toxic and dangerous substances
Noise, hearing and vibration
Broad subject area(s) Physical hazards
Chemical safety
Browse category(ies) Diseases of the ear and hearing damage
Aromatic hydrocarbons
Shipbuliding and ship repair