|Document ID (ISN)||104565|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Lewis R.J., Schnatter A.R., Drummond I., Murray N., Thompson F.S., Katz A.M., Jorgensen G., Nicolich M.J., Dahlman D., ThÚriault G.
||Mortality and cancer morbidity in a cohort of Canadian petroleum workers
||Dec. 2003, Vol.60, No.12, p.918-928. 64 ref.
||Mortality and cancer morbidity were studied in a total of 25,292 Canadian petroleum workers hired between 1964 and 1994 and linked to the Canadian tumour registry and national mortality database. Exposure-response trends were assessed for hydrocarbons (solvents, fuels and lubricants), petroleum coke/spent catalyst and hydrogen sulphide. Overall, external comparison analyses (mortality and incidence) showed deficits for all causes and all malignant neoplasms combined and were consistent with expectation for most malignant and non-malignant sites analysed. Mesothelioma incidence was increased. Statistically significant increases were observed for hydrogen sulphide exposure and a subgroup of accidental deaths as well as for petroleum coke/spent catalyst exposure and lung cancer. However, for lung cancer, the analysis did not adequately control for smoking, was based on small numbers, and exhibited a tenuous exposure-response pattern. The findings for mesothelioma suggest the need for continued attention to asbestos in the petroleum industry. Hydrogen sulphide exposure deserves a closer scrutiny in similarly exposed populations.
||morbidity; mortality; petroleum and natural gas industry; long-term study; cancer
||mesothelioma; Canada; hydrogen sulfide; asbestos; smoking; neoplasms; petroleum coke; confounding factors; cohort study; statistical evaluation; frequency rates; lung cancer
||D - Periodical articles
|Country / State or Province||Canada; USA|
||Mines and quarries
Toxic and dangerous substances
|Broad subject area(s)
Occupational medicine, epidemiology
||Petroleum and natural gas industry