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Document ID (ISN)104449
CIS number 05-663
ISBN(s) 2-551-22699-6
Year 2005
Convention or series no. Etudes et Recherches R-406
Author(s) Carrier G., Brunet R.C., Bouchard M., Gosselin N.H., Dumoulin M.J., Bonvalot Y.
Title Evaluation of human exposure to organophosphates and the associated risks by means of urinary biomarkers
Original title Evaluation de l'exposition humaine aux organophosphorés et des risques associés à l'aide de biomarqueurs urinaires [in French]
Bibliographic information Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST), 505 boul. de Maisonneuve Ouest, Montreal (Quebec) H3A 3C2, Canada, 2005. vii, 73p. Illus. 93 ref. Price: CAD 7.49. Downloadable version (PDF format) free of charge.
Internet access [in French]
Abstract Approximately 200 organophosphates are sold as insecticides and used by workers in agriculture, horticulture, public health pest control, forestry, landscape maintenance and various other sectors. No method currently exists for estimating the quantity actually absorbed following occupational exposure to these substances. Using modelling and a review of existing data, a simple and effective screening tool capable of detecting exposure levels below those causing toxic effects was developed. It consists of a urine biomarker test that evaluates the quantity of organophosphate actually absorbed by the worker. It may be used for prevention programmes, for developing exposure evaluation protocols and for establishing re-entry times after organophosphate exposure.
Descriptors (primary) organophosphorus compounds; insecticides; pesticide spraying; agriculture; exposure evaluation
Descriptors (secondary) toxic effects; report; determination in urine; mathematical models; description of technique; biological threshold limits
Document type E - Books, reports, proceedings
Country / State or ProvinceCanada
Subject(s) Agriculture, fishing, animal husbandry
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Exposure evaluation
Agricultural chemicals