|Document ID (ISN)||104409|
|Convention or series no.
||Etudes et Recherches R-419
||Ostiguy C., Gagné S., Lesage J., Van Tra H., Cloutier Y.
||Development of a highly sensitive analytical method for isocyanates
||Développement d'une méthode d'analyse d'isocyanates à très haute sensibilité [in French]|
||Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST), 505 boul. de Maisonneuve Ouest, Montreal (Quebec) H3A 3C2, Canada, 2005. 44p. Illus. 82 ref. Price: CAD 6.42. Downloadable version (PDF format) free of charge.
||http://www.irsst.qc.ca/files/documents/PubIRSST/R-419.pdf [in French]
||Isocyanates are lung and skin irritants and sensitizers that can cause many diseases, occupational asthma being the most serious. Current methods for determining these substances are often of limited use due to their inadequate sensitivity. This report describes the development of an analytical method to detect low levels of isocyanate in industrial settings. It is based on high-pressure liquid chromatography coupled with mass spectrometry. Sampling is carried out with single-membrane reactive cassettes. The method provides a useful tool for making decisions regarding appropriate personal protective equipment, safer work organization, reassignment of sensitized workers and identification of levels of non-reacted isocyanates in various materials.
||isocyanates; description of technique; determination in air; sampling and analysis
||irritants; mass spectrometry; high-pressure liquid chromatography; sensitizers; personal protective equipment; report
||E - Books, reports, proceedings
|Country / State or Province||Canada|
||Toxic and dangerous substances
|Broad subject area(s)