| Document ID (ISN) | 104322 |
| CIS number |
05-645 |
| ISSN - Serial title |
1047-322X - Applied Occupational and Environmental Hygiene |
| Year |
2002 |
| Convention or series no. |
|
| Author(s) |
Diller W.F. |
| Title |
Frequency and trends of occupational asthma due to toluene diisocyanate: A critical review |
| Bibliographic information |
Dec. 2002, Vol.17, No.12, p.872-877. Illus. 35 ref. |
| Abstract |
Reports and statements on the frequency of occupational asthma due to isocyanates are contradictory. In order to clarify the issue, a critical review of the medical literature of the past half-century worldwide has been performed, with special emphasis on toluene diisocyanate (TDI) as the main representative of the isocyanate family. Nine longitudinal workplace studies of 2751 persons under risk allowed the calculation of incidences of occupational asthma due to TDI. Annual incidences were repeatedly above 5% before 1980, and have decreased to between 0 and 0.7% since 1980. Prevalences of occupational asthma due to TDI were estimated from ten cross-sectional studies, based on 788 persons. Prevalences were repeatedly above 10% before 1985, and have been mostly between 0 and 10% in recent years. |
| Descriptors (primary) |
asthma; tolylene diisocyanate |
| Descriptors (secondary) |
literature survey; statistical trends; frequency rates; long-term study; cross-sectional study |
| Document type |
D - Periodical articles |
| Country / State or Province | Germany |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Diseases of the respiratory system (except for pneumoconiosis & similar)
Isocyanates
Cyano compounds
|
