|Document ID (ISN)||104304|
|ISSN - Serial title
||1076-2752 - Journal of Occupational and Environmental Medicine
|Convention or series no.
||Li G.J., Zhang L.L., Lu L., Wu P., Zheng W.
||Occupational exposure to welding fume among welders: Alterations of manganese, iron, zinc, copper, and lead in body fluids and the oxidative stress status
||Mar. 2004, Vol.46, No.3, p.241-248. Illus. 52 ref.
||Welders in this study were selected from a vehicle manufacturing plant; control subjects were from a nearby food factory. Airborne manganese levels in the breathing zones of welders and controls were 1.45▒1.08mg/m3 and 0.11▒0.07 mg/m3 respectively. Serum levels of manganese and iron in welders were 4.3 fold and 1.9 fold respectively higher than those of controls. Blood lead concentrations in welders increased 2.5 fold, whereas serum zinc levels decreased 1.2 fold, in comparison with controls. Linear regression revealed the lack of associations between blood levels of five metals and welder's age. Furthermore, welders had erythrocytic superoxide dismutase activity and serum malondialdehyde levels 24% less and 78% higher, respectively, than those of controls. These findings suggest that occupational exposure to welding fumes among welders disturbs the homeostasis of trace elements in systemic circulation and induces oxidative stress.
||manganese; metabolic disturbances; welding and cutting; motor vehicle industry; risk factors; welding fumes
||China; iron; zinc; lead; exposure tests; breathing atmosphere; determination in air; determination in blood; case-control study
||D - Periodical articles
|Country / State or Province||China; USA|
||Toxic and dangerous substances
|Broad subject area(s)
Motor vehicle manufacturing industry
Welding and cutting