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Document ID (ISN)104304
CIS number 05-618
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2004
Convention or series no.
Author(s) Li G.J., Zhang L.L., Lu L., Wu P., Zheng W.
Title Occupational exposure to welding fume among welders: Alterations of manganese, iron, zinc, copper, and lead in body fluids and the oxidative stress status
Bibliographic information Mar. 2004, Vol.46, No.3, p.241-248. Illus. 52 ref.
Abstract Welders in this study were selected from a vehicle manufacturing plant; control subjects were from a nearby food factory. Airborne manganese levels in the breathing zones of welders and controls were 1.45▒1.08mg/m3 and 0.11▒0.07 mg/m3 respectively. Serum levels of manganese and iron in welders were 4.3 fold and 1.9 fold respectively higher than those of controls. Blood lead concentrations in welders increased 2.5 fold, whereas serum zinc levels decreased 1.2 fold, in comparison with controls. Linear regression revealed the lack of associations between blood levels of five metals and welder's age. Furthermore, welders had erythrocytic superoxide dismutase activity and serum malondialdehyde levels 24% less and 78% higher, respectively, than those of controls. These findings suggest that occupational exposure to welding fumes among welders disturbs the homeostasis of trace elements in systemic circulation and induces oxidative stress.
Descriptors (primary) manganese; metabolic disturbances; welding and cutting; motor vehicle industry; risk factors; welding fumes
Descriptors (secondary) China; iron; zinc; lead; exposure tests; breathing atmosphere; determination in air; determination in blood; case-control study
Document type D - Periodical articles
Country / State or ProvinceChina; USA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Endocrine diseases
Motor vehicle manufacturing industry
Welding and cutting
Inorganic substances