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Document ID (ISN)104275
CIS number 05-527
ISSN - Serial title 1231-868X - Podstawy i Metody Oceny Środowiska Pracy
Year 2003
Convention or series no.
Author(s) Jakubowski M.
Title Phenol
Original title Fenol [in Polish]
Bibliographic information 2003, Vol.35, No.1, p.87-113. Illus. 78 ref.
Abstract Phenol is used primarily as a feedstock for phenolic resins, caprolactam, xylenols and aniline. The substance is readily absorbed by all routes of exposure. The retention of phenol vapours in the lungs is about 60-80%. The rate of penetration through the skin ranges from 0.08 to 0.3mg/cm2/h. The half-time of excretion of phenol in urine after inhalation exposure is 3.5h. Solutions of phenol are corrosive to the skin and eyes; phenol vapours can irritate the respiratory tract. An RD50 of 624mg/m3 has been reported in mice. Evidence for the carcinogenicity of phenol in laboratory animals was considered by the IARC to be insufficient. Time-weighted average occupational exposure limits vary in different countries between 4 and 19mg/m3. Based on the NOAEL value obtained from an inhalation study in rats, a time-weighted average value of 7.8mg/m3 was proposed. No short-term exposure limit value has been proposed.
Descriptors (primary) phenol; health hazards; toxicology; Poland
Descriptors (secondary) literature survey; threshold limit values; irritants; chemical industry; skin absorption; criteria document; permissible levels; animal experiments; determination of exposure limits; inhalation toxicity; caustic substances
Document type B - Chemical safety information sheets
Country / State or ProvincePoland
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Phenols and phenolic compounds