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Document ID (ISN)104265
CIS number 05-517
ISSN - Serial title 1231-868X - Podstawy i Metody Oceny Środowiska Pracy
Year 2002
Convention or series no.
Author(s) Starek A.
Title Diquat dibromide
Original title Dikwatu dibromek [in Polish]
Bibliographic information 2002, Vol.33, No.3, p.51-65. 31 ref.
Abstract Diquat is a non-selective herbicide mainly used in the form of its soluble dibromide salt, commonly also referred to as "diquat". Ingestion of diquat leads to severe lesions of the gastrointestinal tract, kidneys and liver. This intoxication usually leads to death. The exposure to diquat aerosols may lead to irritation of nasal mucosa and upper airways. The acute toxicity of diquat for laboratory animals is relatively high by all routes of administration. Diquat is possibly also mutagenic and foetotoxic, and may exert a negative effect on the development of offspring. No carcinogenic effects have been reported. The recommended maximum exposure limit of 0.1mg/m3 is based on no observed adverse effect levels (NOAEL) and lowest observed adverse effect levels (LOAEL) derived from long-term studies on rats. The proposed short-term exposure limit value of 0.3mg/m3 is based on the irritant effects of the substance.
Descriptors (primary) Poland; health hazards; toxicology; diquat
Descriptors (secondary) mutagenic effects; embryotoxic effects; herbicides; literature survey; threshold limit values; irritants; criteria document; renal damage; gastrointestinal diseases; permissible levels; animal experiments; determination of exposure limits; agriculture; hepatic damage
Document type B - Chemical safety information sheets
Country / State or ProvincePoland
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Heterocyclic compounds
Genetic factors in reaction to exposures