| Document ID (ISN) | 104264 |
| CIS number |
05-516 |
| ISSN - Serial title |
1231-868X - Podstawy i Metody Oceny Środowiska Pracy |
| Year |
2002 |
| Convention or series no. |
|
| Author(s) |
Sapota A., Ligocka D. |
| Title |
Cyclohexene |
| Original title |
Cykloheksen [in Polish] |
| Bibliographic information |
2002, Vol.33, No.3, p.41-47. 11 ref. |
| Abstract |
Cyclohexene is mainly used in synthesis as an alkylating agent and as a solvent of catalysts during oil extraction. According to the European Union classification, cyclohexene belongs to the group of harmful compounds. There are only sparse data concerning the toxicity of cyclohexene in experimental animals, and a lack of data on its human toxicity. The results of a 6-month inhalation exposure tests on rats, guinea pigs and rabbits were used as the basis for determining the threshold limit values (time-weighted average). Among rats exposed to a concentration of 2010mg/m3, there was a significant decrease of body mass in comparison with the control group. This effect was not observed at lower concentrations. No effects were observed in other animal species subjected to the same experiment. Consequently, it is recommended that the current threshold limit (time-weighted average) and short-term exposure limit values of 300 mg/m3 and 900mg/m3 respectively should remain without change. |
| Descriptors (primary) |
Poland; health hazards; toxicology; cyclohexene |
| Descriptors (secondary) |
literature survey; alkylating substances; threshold limit values; criteria document; permissible levels; animal experiments; determination of exposure limits; solvents |
| Document type |
B - Chemical safety information sheets |
| Country / State or Province | Poland |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Aliphatic and alicyclic hydrocarbons
|
