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Document ID (ISN)104125
CIS number 05-376
ISSN - Serial title 0019-8366 - Industrial Health
Year 2003
Convention or series no.
Author(s) Kishimoto T., Ohnishi K., Saito Y.
Title Clinical study of asbestos-related lung cancer
Bibliographic information Apr. 2003, Vol.41, No.2, p.94-100. Illus. 37 ref.
Internet access http://www.niih.go.jp/en/indu_hel/2003/pdf/IH41_14.pdf [in English]
Abstract The characteristics of 120 patients with primary lung cancer suspected to be induced by exposure to asbestos were analysed. Most patients were male and the age ranged from 47 to 87 years with a median of 70 years. No particular tendency was observed in the histological types of the lung cancer. Forty patients were heavy smokers. Most of the patients had been exposed to asbestos in shipyards, the construction industry and ironworks. The term of asbestos exposure was from two to 60 years with a median 27 years. Lung cancers appeared after 15 to 69 years with a median 43 years from the initial exposure to asbestos. Lung cancer was accompanied by asbestosis in 35 patients and by pleural plaques in 77, with 22 patients having both asbestosis and pleural plaques. The number of asbestos bodies per 5g wet lung tissue for 72 patients whose lung tissues were obtained from autopsy or surgery was more than 150. In a group of 32 patients, 14 were exposed to crocidolite fibres, ten to amosite and eight to chrysotile.
Descriptors (primary) Japan; lung cancer; asbestos
Descriptors (secondary) amosite; chrysotile; crocidolite; smoking; iron and steel industry; asbestosis; shipyards; building industry; length of exposure; pleural calcification
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Asbestos
Diseases of the respiratory system (except for pneumoconiosis & similar)