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Document ID (ISN)104040
CIS number 05-384
Year 2004
Convention or series no. DHHS (NIOSH) Publication No.2005-106
Title Mixed exposures research agenda - A report by the NORA mixed exposures team
Bibliographic information Publications Dissemination, National Institute for Occupational Safety and Health (NIOSH), 4676 Columbia Parkway, Cincinnati, OH 45226-2002, USA, Dec. 2004. x, 42p. 51 ref.
Internet access [in English]
Abstract Research has shown that physiological interactions from mixed exposures can lead to an increase in severity of the harmful effect. For example, dual exposure to noise and toluene results in a higher risk of hearing loss than exposure to either stressor alone. Exposure to carbon monoxide and methylene chloride produces elevated levels of carboxyhaemoglobin, reducing the blood's ability to carry oxygen in the body. The problem of mixed exposures is multifaceted, given the large number of combinations that occur in a variety of workplaces. This report was prepared by a team formed from experts inside and outside the public sector that examined the literature, tracked ongoing research, identified significant research gaps and set priorities for future research.
Descriptors (primary) USA; hazard evaluation; exposure; risk factors; research; synergism
Descriptors (secondary) literature survey; epidemiology; experimental determination; mathematical models; glossary; exposure evaluation
Document type E - Books, reports, proceedings
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation