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CISDOC database

Document ID (ISN)104022
CIS number 05-364
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2004
Convention or series no.
Author(s) Whitehouse A.C.
Title Asbestos-related pleural disease due to tremolite associated with progressive loss of lung function: Serial observations in 123 miners, family members, and residents of Libby, Montana
Bibliographic information Sep. 2004, Vol.46, No.3, p.219-225. Illus. 27 ref.
Abstract The community of Libby, Montana was recently the focus of national attention following a widespread amphibole contamination associated with vermiculite mining and processing. Patients who had occupational and non-occupational exposure to asbestos in Libby were evaluated for progressive loss of pulmonary function. Of the 123 patients evaluated, the average annual age-corrected losses were 3.2% for vital capacity, 2.3% for total lung capacity and 3.3% for carbon monoxide diffusion. All these patients had predominantly pleural changes with minimal to no interstitial disease. The study demonstrates a progressive loss of pulmonary function in patients exposed to tremolite asbestos.
Descriptors (primary) Montana; asbestos; asbestos mining; pulmonary function; pleural diseases
Descriptors (secondary) tremolite asbestos; USA; pleural thickening; amphibole; vermiculite; radiological changes; long-term exposure; respiratory function tests; spirometry; chest radiography; maximal expiratory flow
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Mines and quarries
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Asbestos
Mining and quarrying