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CISDOC database

Document ID (ISN)104018
CIS number 05-338
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2004
Convention or series no.
Author(s) Zuskin E., Mustajbegovic J., Schachter E.N., Kern J., Deckovic-Vukres V., Pukarin-Cvetkovic J., Nola-Premec I.A.
Title Respiratory findings in pharmaceutical workers
Bibliographic information Nov. 2004, Vol.46, No.5, p.472-479. 26 ref.
Abstract Pharmaceutical workers may be at risk of developing respiratory problems as a result of their work environment. This study investigated 163 female and 35 male workers employed in a pharmaceutical plant producing primarily antibiotics, in order to characterize the risk of this environment. 113 controls were selected from a food packing facility. Chronic respiratory symptoms were recorded by using the British Medical Research Council questionnaire. Acute symptoms which developed during the work shift were recorded and participants were subjected to spirometry tests. A significantly higher prevalence of chronic respiratory symptoms was recorded among pharmaceutical workers (compared to controls), the highest being for sinusitis, nasal catarrh, and dyspnoea. There was also a high prevalence of acute symptoms recorded during the work shift. The most significant risk factors for these respiratory findings were smoking and length of time worked in the pharmaceutical industry, particularly in men.
Descriptors (primary) antibiotics; respiratory diseases; pharmaceutical industry; health hazards; risk factors; respirable dust
Descriptors (secondary) rhinitis; shift work; smoking; sinusitis; dyspnoea; pulmonary function; chronic respiratory diseases; questionnaire survey; case-control study; sex-linked differences; length of exposure; frequency rates; hazard evaluation
Document type D - Periodical articles
Country / State or ProvinceCroatia; USA
Subject(s) Chemicals, plastics and rubber
Broad subject area(s) Industries and occupations
Occupational medicine, epidemiology
Browse category(ies) Pharmaceutical industry
Diseases of the respiratory system (except for pneumoconiosis & similar)