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Document ID (ISN)103977
CIS number 05-183
ISSN - Serial title 1877-7856 - Encyclopédie médico-chirurgicale
Year 2004
Convention or series no. Fascicule 16536 A 10, 4-2004
Author(s) Boillat M.A.
Title Organic mental disorders of toxic origin
Original title Troubles mentaux organiques d'origine toxique [in French]
Bibliographic information Toxicologie-Pathologie professionnelle, 4th Quarter 2004, No.145, 5p. 40 ref.
Abstract Solvents are among the substances that are most frequently involved in the occurrence of organic mental disorders of toxic origin. While acute effects such as reversible pre-narcotic disorders are unanimously recognized within the scientific community, chronic effects due to several years of low-level exposures are the subject of scientific debate. From the 1970s onwards, various studies have described an organic disorder syndrome (chronic toxic encephalitis). Some questions concerning the conditions of occurrence of this syndrome and its relationship with the level, duration and nature of exposure to solvents remain unanswered. Diagnosis is difficult because of the lack of specificity. Once exposure is confirmed and other mental or psychiatric disorders excluded, diagnosis rests on the presence of thymic disorders together with memory loss, concentration difficulties and sensorimotor disorders, with the deterioration of cortical functions appearing in later stages.
Descriptors (primary) neurotoxic effects; France; solvents; mental disorders; toxic substances; chronic diseases
Descriptors (secondary) literature survey; cognitive performance; prognosis; encephalopathy; symptoms; data sheet; diagnosis; length of exposure; medical supervision; encyclopaedia; disturbances of memory
Document type F - Information notes, codes of practice, standards
Country / State or ProvinceFrance
Subject(s) Occupational pathology
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the nervous system
Mental health