|Document ID (ISN)||103901|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Shiau C.Y., Wang J.D., Chen P.C.
||Decreased fecundity among male lead workers
||Nov. 2004, Vol.61, No.11, p.915-923. Illus. 42 ref.
||The objective of this study was to investigate time to pregnancy (TTP) in wives of male workers exposed to lead in order to determine the dose-response relation between blood lead and decreased fecundity. 163 currently-employed married male lead battery workers were classified into five categories of exposure based on questionnaire information and annual blood lead levels. Information pertaining to the TTP was collected using personal interviews of men and their spouses. Fecundity ratios (FRs) were calculated using regression techniques. After controlling for other factors associated with TTP, a dose-response relation was observed between blood lead level and TTP. The measured FRs were 0.90, 0.72, 0.52 and 0.40 for concurrent blood lead levels of <20, 20-29, 30-39, and >40µg/dl, respectively. These results corroborate the hypothesis that a raised blood lead level affects fecundity.
||antifertility effects; dose-response relationship; battery and dry cell manufacture; lead
||male workers; Taiwan (China); determination in blood; questionnaire survey; statistical evaluation; exposure evaluation
||D - Periodical articles
|Country / State or Province||Taiwan (China)|
||Toxic and dangerous substances
|Broad subject area(s)
Occupational medicine, epidemiology
||Antifertility and prenatal effects
Genetic factors in reaction to exposures
Manufacturing of electrical appliances and equipment
Lead and compounds