ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)103901
CIS number 05-162
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2004
Convention or series no.
Author(s) Shiau C.Y., Wang J.D., Chen P.C.
Title Decreased fecundity among male lead workers
Bibliographic information Nov. 2004, Vol.61, No.11, p.915-923. Illus. 42 ref.
Abstract The objective of this study was to investigate time to pregnancy (TTP) in wives of male workers exposed to lead in order to determine the dose-response relation between blood lead and decreased fecundity. 163 currently-employed married male lead battery workers were classified into five categories of exposure based on questionnaire information and annual blood lead levels. Information pertaining to the TTP was collected using personal interviews of men and their spouses. Fecundity ratios (FRs) were calculated using regression techniques. After controlling for other factors associated with TTP, a dose-response relation was observed between blood lead level and TTP. The measured FRs were 0.90, 0.72, 0.52 and 0.40 for concurrent blood lead levels of <20, 20-29, 30-39, and >40Ág/dl, respectively. These results corroborate the hypothesis that a raised blood lead level affects fecundity.
Descriptors (primary) antifertility effects; dose-response relationship; battery and dry cell manufacture; lead
Descriptors (secondary) male workers; Taiwan (China); determination in blood; questionnaire survey; statistical evaluation; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceTaiwan (China)
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Manufacturing of electrical appliances and equipment
Lead and compounds
Inorganic substances