ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)103862
CIS number 05-159
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2004
Convention or series no.
Author(s) Swaen G.M.H., Bloemen L.J.N., Twisk J., Scheffers T., Slangen J.J.M., Collins J.J., ten Berge W.F.J.P.
Title Mortality update of workers exposed to acrylonitrile in the Netherlands
Bibliographic information July 2004, Vol.46, No.7, p.691-698. 22 ref.
Abstract To study the possible carcinogenic effects of acrylonitrile, the follow up of a cohort of 2842 acrylonitrile workers was updated. The comparison group consisted of 3961 unexposed workers from a fertilizer plant. Industrial hygiene assessments quantified past exposure to acrylonitrile, 8-hour averages as well as peak exposure, the use of personal protective equipment, and exposure to other potential carcinogenic agents. Standardized mortality ratios were calculated to adjust for the effect of age distribution, length of follow-up and temporal changes in background mortality rates. Cumulative dose-effect relations were determined for three exposure categories and three latency periods. The results show that no cancer excess seems related to exposure to acrylonitrile.
Descriptors (primary) acrylonitrile; risk factors; cancer; mortality
Descriptors (secondary) carcinogens; Netherlands; exposure evaluation; case-control study; frequency rates; personal protective equipment; long-term study; dose-response relationship; cohort study
Document type D - Periodical articles
Country / State or ProvinceNetherlands
Subject(s) Occupational pathology
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Cyano compounds