| Document ID (ISN) | 103862 |
| CIS number |
05-159 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2004 |
| Convention or series no. |
|
| Author(s) |
Swaen G.M.H., Bloemen L.J.N., Twisk J., Scheffers T., Slangen J.J.M., Collins J.J., ten Berge W.F.J.P. |
| Title |
Mortality update of workers exposed to acrylonitrile in the Netherlands |
| Bibliographic information |
July 2004, Vol.46, No.7, p.691-698. 22 ref. |
| Abstract |
To study the possible carcinogenic effects of acrylonitrile, the follow up of a cohort of 2842 acrylonitrile workers was updated. The comparison group consisted of 3961 unexposed workers from a fertilizer plant. Industrial hygiene assessments quantified past exposure to acrylonitrile, 8-hour averages as well as peak exposure, the use of personal protective equipment, and exposure to other potential carcinogenic agents. Standardized mortality ratios were calculated to adjust for the effect of age distribution, length of follow-up and temporal changes in background mortality rates. Cumulative dose-effect relations were determined for three exposure categories and three latency periods. The results show that no cancer excess seems related to exposure to acrylonitrile. |
| Descriptors (primary) |
acrylonitrile; risk factors; cancer; mortality |
| Descriptors (secondary) |
carcinogens; Netherlands; exposure evaluation; case-control study; frequency rates; personal protective equipment; long-term study; dose-response relationship; cohort study |
| Document type |
D - Periodical articles |
| Country / State or Province | Netherlands |
| Subject(s) |
Occupational pathology
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Cyano compounds
|
