|Document ID (ISN)||103360|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Biagini R.E., Sammons D.L., Smith J.P., Page E.H., Snawder J.E., Striley C.A.F., MacKenzie B.A.
||Determination of serum IgG antibodies to Bacillus anthracis protective antigen in environmental sampling workers using a fluorescent covalent microsphere immunoassay
||Aug. 2004, Vol.61, No.8, p.703-708. Illus. 28 ref.
||To evaluate potential exposure to Bacillis anthracis (Ba) spores in 28 sampling and decontamination workers in the aftermath of an anthrax terror attack in October 2001, serum Ba anti-protective antigen (PA) specific IgG antibodies were determined using a newly developed fluorescent covalent microsphere immunoassay (FCMIA). Four serum samples gave positive anti-PA IgG results, from the pre-entry and follow up samples of two workers who had received their last dose of anthrax vaccine in 2000. It appears that the workers either had insufficient exposure to Ba spores to cause the production of anti-PA IgG antibodies or they were exposed to anthrax spores without producing antibody. The FCMIA appears to be a fast, sensitive, accurate and precise method for the measurement of anti-PA IgG antibodies.
||anthrax; terrorism; exposure tests; biological hazards
||spores; immunoglobulins; antigens; determination in blood; exposure evaluation; sampling and analysis; vaccination; antibodies
||D - Periodical articles
|Country / State or Province||USA|
||Commerce, services, offices
|Broad subject area(s)
||Bacterial and parasitic diseases
Violence and terrorism