|Document ID (ISN)||103341|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Attfield M.D., Costello J.
||Quantitative exposure-response relationship for silica dust and lung cancer in Vermont granite workers
||Feb. 2004, Vol.45, No.2, p.129-138. Illus. 27 ref.
||Exposure evaluation data for the years 1924 to 1977 were analysed in conjunction with mortality data to examine quantitative exposure-response for silica, lung cancer and other lung diseases in a cohort of granite workers in the U.S. state of Vermont. The findings indicated a clear relationship of lung cancer, tuberculosis, pneumoconiosis, non-malignant lung disease and kidney cancer with cumulative exposure. An exposure to silica of 0.05mg/m3 from age 20 to 64 was associated with a lifetime excess risk of lung cancer for white males of 27/1000. The results of this study of workers exposed almost exclusively to silica and no other major occupational confounding exposures indicate a clear exposure-response for lung cancer.
||Vermont; occupational diseases; granite; quarrying industry; lung cancer; respirable dust; silica
||USA; tuberculosis; renal cancer; lung diseases; statistical evaluation; hazard evaluation; cohort study; dose-response relationship; pneumoconiosis
||D - Periodical articles
|Country / State or Province||USA|
||Mines and quarries
|Broad subject area(s)
Occupational medicine, epidemiology
||Diseases of the respiratory system (except for pneumoconiosis & similar)
Mining and quarrying
Bacterial and parasitic diseases