| Document ID (ISN) | 103155 |
| CIS number |
04-153 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
2003 |
| Convention or series no. |
|
| Author(s) |
Fiedler N., Weisel C., Lynch R., Kelly-McNeil K., Wedeen R., Jones K., Udasin I., Ohman-Strickland P., Gochfeld M. |
| Title |
Cognitive effects of chronic exposure to lead and solvents |
| Bibliographic information |
Oct. 2003, Vol.44, No.4, p.413-423. Illus. 55 ref. |
| Abstract |
The purpose of this study was to investigate the cognitive function effects of chronic occupational exposure to lead and solvents. Based on tibial bone lead and occupational history of solvent exposure, subjects were classified into the following exposure groups: "lead" (N=40), "solvent" (N=39) and "lead/solvent" (N=45), as well as an unexposed control group (N=33). All subjects completed tests to assess concentration, motor skills, memory and mood. Relative to controls, the "lead", "solvent", and "lead/solvent" groups performed significantly more poorly on a test of verbal memory, while the "lead" and "lead/solvent" groups were slower than the solvent and control groups on a task of processing speed. Bone lead was a significant predictor of information processing speed and latency of response while solvent exposure was a significant predictor of verbal learning and memory. |
| Descriptors (primary) |
neurotoxic effects; cognitive performance; long-term exposure; solvents; lead |
| Descriptors (secondary) |
speed of work; disturbances of memory; determination in bones; case-control study; mental attitude |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Diseases of the nervous system
Lead and compounds
|
