ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)102776
CIS number 03-1631
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2004
Convention or series no.
Author(s) Yu I.T.S., Lee N.L., Zhang X.H., Chen W.Q., Lam Y.T., Wong T.W.
Title Occupational exposure to mixtures of organic solvents increases the risk of neurological symptoms among printing workers in Hong Kong
Bibliographic information Apr. 2004, Vol.46, No.4, p.323-330. 29 ref.
Abstract The health effects of low-dose occupational exposure to organic solvents remains unclear. A cross-sectional survey was conducted among 762 male printing workers to assess the effects of exposure to mixtures of n-hexane, toluene, isopropyl alcohol and benzene on neurological and other symptoms. After adjusting for age, smoking, alcohol consumption, past exposure history, working hours and shift work, it was found that exposure to solvent mixtures was significantly associated with the total number of neurological symptoms and with the prevalence of specific symptoms of the nervous system and mucous membrane irritation. The adjusted odds ratio of neurovegetative lability (1.7-5.9), abnormal or reduced smell (1.6-4.1), memory loss (1.8) and mucous membrane irritation symptoms (1.5-4.6) significantly increased in the exposed group, especially when the summation index of exposure exceeded unity.
Descriptors (primary) neurotoxic effects; Hong Kong; risk factors; mixtures; organic solvents; printing industry
Descriptors (secondary) hexane; benzene; toluene; isopropyl alcohol; irritation; cross-sectional study; neurovegetative disorders; loss of smell; hazard evaluation; mucous membranes; disturbances of memory
Document type D - Periodical articles
Country / State or ProvinceHong Kong
Subject(s) Paper-making and printing
Broad subject area(s) Occupational medicine, epidemiology
Chemical safety
Browse category(ies) Printing, photography and photocopying industry
Diseases of the nervous system