|Document ID (ISN)||102737|
|ISSN - Serial title
||0105-1873 - Contact Dermatitis
|Convention or series no.
||Korinth G., G÷en T., Lakemeyer M., Broding H.C., Drexler H.
||Skin strain and its influence on systemic exposure to a glycol ether in offset printing workers
||Nov. 2003, Vol.49, No.5, p.248-254. Illus. 31 ref.
||The aim of this study was to show whether systemic exposure to glycol ether is higher among printing workers with skin lesions. 28 male printers exposed to 2-(2-butoxyethoxy)ethanol (BEE) were interviewed on their workplace exposure by means of a standardized questionnaire. The systemic exposure was determined by biological monitoring of the main metabolite of BEE (butoxyethoxyacetic acid, BEAA) in urine. Furthermore, a clinical examination of the skin was also carried out, together with measurements of transepidermal water loss, capacitance and skin surface pH. Erythema and scaliness were the most important factors showing an effect on dermal absorption. The mean urinary BEAA excretions for printers with skin lesions on the hands were higher (20.62mg/L for scaliness and 14.40mg/L for erythema) compared to levels for printers without detectable skin lesions (12.08mg/L for scaliness and 13.03mg/L for erythema).
||diethylene glycol butyl ether; skin absorption; organic solvents; skin diseases; offset printing
||erythema; exposure evaluation; determination in urine; urinary metabolites; questionnaire survey
||D - Periodical articles
|Country / State or Province||Germany|
||Paper-making and printing
|Broad subject area(s)
Printing, photography and photocopying industry