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Document ID (ISN)102279
CIS number 03-1091
ISBN(s) 92-4-153050-2
Year 2003
Convention or series no. CICAD No.50
Author(s) Fisher J.F.
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
Title Elemental mercury and inorganic mercury compounds: Human health aspects
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2003. iv, 61p. 298 ref.
Internet access 03-1091.pdf [in English]
http://www.who.int/ipcs/publications/cicad/en/cicad50.pdf [in English]
Abstract Conclusions of this criteria document: mild subclinical signs of central nervous toxicity can be observed among workers exposed to elemental mercury at a concentration of 20µg/m3 or above for several years. Neurological and behavioural disorders have been observed following inhalation of elemental mercury vapour or dermal application of inorganic mercury-containing medicinal products. The primary effect of long-term oral exposure to low amounts of inorganic mercury compounds is renal damage; immunological effects have also been shown. Data from animal studies indicate that mercuric chloride has some carcinogenic activity in male rats; parenteral administration of inorganic mercury compounds is embryotoxic and teratogenic in rodents. Inorganic mercury compounds seem to interact with and damage DNA in vitro.
Descriptors (primary) IPCS; health hazards; toxicology; mercury and compounds
Descriptors (secondary) toxic effects; criteria document; literature survey; ILO; UNEP; WHO; mercuric chloride; mercury chloride; mercury; mercuric acetate; renal damage; ecotoxicology; animal experiments; lethal concentration 50; mercury sulfide; neurotoxic effects
Document type B - Chemical safety information sheets
Country / State or ProvinceUSA; WHO
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Mercury and compounds
Inorganic substances