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Document ID (ISN)101832
CIS number 03-762
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2003
Convention or series no.
Author(s) Geier J., Lessmann H., Uter W., Schnuch A.
Title Occupational rubber glove allergy: Results of the Information Network of Departments of Dermatology (IVDK), 1995-2001
Bibliographic information Jan. 2003, Vol.48, No.1, p.39-44. Illus. 23 ref.
Abstract Among the patients with occupational contact dermatitis registered in the Information Network of Departments of Dermatology (known under the German acronym IDVK) during the years 1995-2001, 2047 were patch tested for suspected rubber glove allergy. Reaction frequencies to thiurams, dithiocarbamates, mercaptobenzothiazole (MBT) and its derivatives, thioureas, and 1,3-diphenylguanidine (1,3-DPG) were analysed. Thiurams were by far the most frequent allergens in these patients (16.2% positive reactions). Although manufacturers have increased the use of dithiocarbamates and MBT derivatives in rubber glove production in recent years, these allergens elicited positive reactions in only about 3% of the patients tested, and showed no increasing trend. Thioureas and 1,3-DPG are not widely used in rubber glove production, and play only a minor role in rubber glove contact allergy. Most of the positive reactions to 1,3-DPG are probably false-positive, irritant reactions.
Descriptors (primary) protective gloves; skin diseases; natural rubber; allergens
Descriptors (secondary) irritants; Germany; diphenylguanidine; benzothiazolethiol; tetramethylthiuram disulfide; medical examinations; inhalation; skin allergies; eczema; skin tests; dithiocarbamates
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Hand and arm protection
Skin diseases