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Document ID (ISN)101707
CIS number 03-760
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2003
Convention or series no.
Author(s) Clary T., Ritz B.
Title Pancreatic cancer mortality and organochlorine pesticide exposure in California, 1989-1996
Bibliographic information Mar. 2003, Vol.43, No.3, p.306-313. Illus. 29 ref.
Abstract Earlier studies have suggested a possible link between organochlorine pesticides and the occurrence of pancreatic cancers. California maintains a death file and a pesticide reporting system that allows examination of this relationship in residents of high-use areas. Mortality odds ratios were used to compare deaths from pancreatic cancer from 1989 to 1996 with a random sample of non-cancer deaths. Using pesticide data for three agricultural counties, 102 postal codes were classified for pesticide usage from 1972 to 1989. The effect of pesticide applications were estimated by logistic regression for each postal code after controlling for possible confounders. Among long-term residents, pancreatic cancer mortality was elevated for those living in postal codes with the highest use of 1,3-dichloropropene, captafol, pentachloronitrobenzene and dieldrin. No dose-response relationship was observed.
Descriptors (primary) California; dichloropropene; chlorinated organic compounds; risk factors; pesticides; tumour of the pancreas; cancer; mortality
Descriptors (secondary) USA; dieldrin; quintozene; frequency rates; exposure evaluation; statistical evaluation; captafol
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Endocrine diseases
Halogenated hydrocarbons
Agricultural chemicals