|Document ID (ISN)||101679|
|ISSN - Serial title
||0170-2327 - Ergo-Med
|Convention or series no.
||Jung D., Böttiger A.
||Mutagenicity and teratogenicity studies during the handling of cytostatic drugs
||Studien zur Mutagenität und Teragenität beim Umgang mit Zytostatika [in German]|
||Nov.-Dec. 2002, Vol.26, No.6, p.162-166. Illus. 3 ref.
||Three studies involving hospital pharmacists were carried out in order to establish mutagenic and teratogenic hazards during the handling of cytostatic drugs. Sister chromatid exchanges, breaks in DNA strands, alkyl guanidine transferase levels and mitosis levels were evaluated. Under working conditions that include the most recent technologies (work in laminar flow safety cabinets), no significant differences were observed between exposed and non-exposed groups.
||mutagens; antineoplastic drugs; teratogenic effects; hospitals; manual handling
||mitosis; DNA; expectant mothers; case-control study; chromosome changes; exposure evaluation
||D - Periodical articles
|Country / State or Province||Germany|
||Toxic and dangerous substances
|Broad subject area(s)
||Antifertility and prenatal effects
Health care services
Genetic factors in reaction to exposures