|Document ID (ISN)||101645|
|Convention or series no.
||Czerczak S., Fishbein L.
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
||Arsine: Human health aspects
||World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2002. iv, 29p. 107 ref.
||http://www.who.int/ipcs/publications/cicad/en/cicad47.pdf [in English]
||Conclusions of this criteria document: the target organ of arsine poisoning is the haematopoietic system. Arsine induces haemolysis causing haemoglobinuria and subsequent kidney damage. Myocardial and pulmonary failures are other causes of death. Aneamia and increased leucocytosis is observed at various degrees. There are no data on the carcinogenicity or mutagenicity of arsine to humans or experimental animals.
||IPCS; toxicology; arsine
||toxic effects; literature survey; ILO; UNEP; WHO; anaemia; criteria document; haematuria; ecotoxicology; animal experiments; lethal concentration 50; haematotoxic effects; nephrotoxic effects; haemolysis
||B - Chemical safety information sheets
|Country / State or Province||Poland; USA; WHO|
||Toxic and dangerous substances
|Broad subject area(s)
||Arsenic and compounds