|Document ID (ISN)||101644|
|Convention or series no.
||Newhook R., Meek M.E., Caldbick D.
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
||World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2002. iv, 42p. Illus. 192 ref.
||http://www.who.int/ipcs/publications/cicad/en/cicad46.pdf [in English]
||Conclusions of this criteria document: the nervous system appears to be the critical target for carbon disulfide (reduced conduction velocity and impaired psychomotor performance). Other effects include irritation of the skin and eyes, alterations in serum lipids and blood pressure that are associated with increased risk of cardiovascular disease, systemic opthalmological effects (effects on colour vision, damage of blood vessels of the retina) and, with higher exposures, increased mortality from heart disease. Several reports indicate decreased libido and/or impotence in males occupationally exposed to high concentrations, but there is no evidence of adverse reproductive effects. Data from animal studies indicate that carbon disulfide is embryotoxic and foetotoxic; no carcinogenic effects have been reported.
||IPCS; toxicology; carbon disulfide
||toxic effects; literature survey; irritants; ILO; UNEP; criteria document; skin absorption; cardiovascular disorders; animal experiments; neurological effects; ophthalmotoxic effects; WHO
||B - Chemical safety information sheets
|Country / State or Province||WHO|
||Toxic and dangerous substances
|Broad subject area(s)
||Inorganic sulfur compounds