|Document ID (ISN)||101643|
|Convention or series no.
||Gomes R., Liteplo R., Meek M.E.
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
||Ethylene glycol: Human health aspects
||World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2002. iv, 38p. Illus. 134 ref.
||http://www.who.int/ipcs/publications/cicad/en/cicad45.pdf [in English]
||Conclusions of this criteria document: data available from acute poisoning indicate that the kidney is a critical organ for the toxicity of ethylene glycol; neurological and neurobehavioural disorders have been reported but available data are inadequate to assess potential neurological and immunological effects associated with ethylene glycol. Data from animal studies indicate that ethylene glycol has nephrotoxic and teratogenic effects; there is evidence of reproductive toxicity in mice (at very high doses) but not in rats.
||IPCS; toxicology; ethylene glycol
||toxic effects; literature survey; ILO; UNEP; criteria document; animal experiments; neurological effects; nephrotoxic effects; WHO
||B - Chemical safety information sheets
|Country / State or Province||Canada; WHO|
||Toxic and dangerous substances
|Broad subject area(s)