|Document ID (ISN)||101581|
|ISSN - Serial title
||0105-1873 - Contact Dermatitis
|Convention or series no.
||Frick M., Isaksson M., Bj÷rkner B., HindsÚn M., PontÚn A., Bruze M.
||Occupational allergic contact dermatitis in a company manufacturing boards coated with isocyanate lacquer
||May 2003, Vol.48, No.5, p.255-260. 16 ref.
||Following the introduction of a lacquer based on diphenylmethane-4,4'-diisocyanate at a company producing flooring laminate boards, there was an outbreak of work-related skin lesions among workers. In five workers, patch testing was performed with a standard series, an isocyanate series and products present in the work environment. Among workers tested with the lacquer, contact allergy was found with concurrent reactions to 4,4'-diaminodiphenylmethane (MDA). Occupational contact with isocyanates should not be exclusively focused upon respiratory hazards, as this report shows that skin contamination probably increases the risk of developing contact allergy to isocyanates and isocyanate-related substances. When aiming at diagnosing contact allergy to isocyanates, it is desirable to perform a late reading, as positive reactions appear late. MDA appears to be a good marker for isocyanate hypersensitivity.
||diphenylmethane diisocyanate; lacquers; dermatitis; flooring
||allergens; methylenedianiline; case study; hypersensitivity; eczema; delayed effects; skin tests; skin allergies
||D - Periodical articles
|Country / State or Province||Sweden|
|Broad subject area(s)