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Document ID (ISN)101485
CIS number 03-322
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2003
Convention or series no.
Author(s) Crippa M., Belleri L., Mistrello G., Carsana T., Neri G., Alessio L.
Title Prevention of latex allergy among health care workers: Evaluation of the extractable latex protein content in different types of medical gloves
Bibliographic information July 2003, Vol.44, No.1, p.24-31. Illus. 20 ref.
Internet access 03-0322.pdf [in English]
Abstract Since the 1980s, there has been increased use of latex gloves by health care workers and a concomitant increase of irritant and allergic reactions. The total protein content and the latex allergenic protein content of 29 different types of medical gloves commonly used in a hospital were evaluated with the Lowry modified method and the RAST inhibition assay in glove samples and extracts to acquire information useful for preventing latex allergy in hospital personnel. The highest concentrations of total proteins and allergenic latex proteins were found in examination powdered latex gloves and in surgical powdered latex gloves; a significant amount of latex proteins was found in some brands of nitrile gloves. The clear association between the total protein levels and the allergenic latex protein levels suggests that the gloves with highest total protein content have the greatest allergenic potential. Therefore, it is recommended that manufacturing companies provide package inserts including the total protein contents and possibly allergenic latex protein levels They should declare whether they have added latex to their nitrile glove formulation. RAST-inhibition assays directly on glove samples instead of glove extract seems to be a highly reliable and faster alternative for the evaluation of the allergenic potential of latex gloves.
Descriptors (primary) proteins; protective gloves; hospitals; latex; allergens
Descriptors (secondary) nitriles; allergies; equipment testing; immunology; health care personnel
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Commerce, services, offices
Broad subject area(s) Chemical safety
Browse category(ies) Hand and arm protection
Health care services