|Document ID (ISN)||101268|
|ISSN - Serial title
||0340-0131 - International Archives of Occupational and Environmental Health
|Convention or series no.
||Wang V.S., Lee M.T., Chiou J.Y., Guu C.F., Wu C.C., Wu T.N., Lai J.S.
||Relationship between blood lead levels and renal function in lead battery workers
||Oct. 2002, Vol.75, No.8, p.569-575. 40 ref.
||The aim of this study was to investigate the correlation between blood lead (PbB) levels and renal function indices of blood-urea nitrogen (BUN), serum creatinine (SC) and uric acid (UA) among lead battery industry workers with exposure to lead. 229 workers of both genders from two lead battery factories were recruited in this cross-sectional study. Personal airborne and blood samples were collected on the same day. A positive correlation between PbB levels and individual renal function index of BUN, SC, and UA was found. PbB levels and renal function indices showed significant difference between male and female workers. An increment of 10µg/dL PbB produced an increase of 0.62mg/dL BUN and an increase of 0.085mg/dL UA. For all workers, there was a significant dose-response relationship between PbB and BUN and UA levels. It is suggested that blood-urea nitrogen and uric acid be considered as indicators of renal dysfunction in lead-exposed workers.
||renal dysfunction; exposure tests; battery and dry cell manufacture; lead
||creatinine; uric acid; urea; exposure evaluation; determination in blood; renal function tests; sex-linked differences; dose-response relationship; determination in air; cross-sectional study
||D - Periodical articles
|Country / State or Province||Taiwan (China)|
||Toxic and dangerous substances
|Broad subject area(s)
||Diseases of the kidney and the urinary system
Manufacturing of electrical appliances and equipment
Lead and compounds