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Document ID (ISN)101256
CIS number 03-307
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2002
Convention or series no.
Author(s) Jamal G.A., Hansen S., Pilkington A., Buchanan D., Gillham R.A., Abdel-Azis M., Julu P.O.O., Al-Rawas S.F., Hurley F., Ballantyne J.P.
Title A clinical neurological, neurophysiological, and neuropsychological study of sheep farmers and dippers exposed to organophosphate pesticides
Bibliographic information July 2002, Vol.59, No.7, p.434-441. 28 ref.
Abstract The objective of this study was to highlight clinical diseases of subjects with abnormal indices of peripheral neuropathy identified in an earlier field study of sheep farmers exposed to organophosphate pesticides during dipping. This case-control study (79 subjects) was nested within the cross sectional study (685 subjects) of sheep farmers from the field study. Subjects were divided into three groups on the basis of the absence, possibility or certainty of signs of neuropathy. The incidence of clinical neuropathy based on nerve conduction measurements was 7% in the "without neuropathy" group and 52% in the probable or definite neuropathy group. Sensory abnormalities were found more often than motor deficits. Small diameter nerve fibres were also affected more than large fibres. Increasing severity of neuropathy was associated with anxiety and depression as measured in the neuropsychological tests.
Descriptors (primary) neurotoxic effects; livestock rearing; organophosphorus compounds; nerve lesions; neurological effects; neuropsychic effects; symptoms
Descriptors (secondary) nervous function tests; nervous conduction disorders; sensory aptitude; psychological tests; cross-sectional study; electromyography; case-control study
Document type D - Periodical articles
Country / State or ProvinceUnited Kingdom
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the nervous system
Livestock rearing