|Document ID (ISN)||101050|
|ISSN - Serial title
||1219-1221 - Central European Journal of Occupational and Environmental Medicine
|Convention or series no.
||Ibrahim K.S., Ahmed S.B.
||Male endocrine dysfunction in lead smelter workers
||2002, Vol.8, No.1, p.31-38. 36 ref.
||Evidence of the effect of occupational exposure to lead on the male endocrine function is controversial. This study evaluated the primary (testicular) and secondary (hypothalamo-pituitary-testicular) effects of exposure to lead in 69 workers employed for an average of 16 years and in 40 non-exposed workers. The mean blood lead concentration was 42.92▒4.89Ág/dL in the exposed workers and 29.5▒ 5.3Ág/dL in the control group. Concentrations of serum luteinizing hormone (LH) and follicle stimulating hormone (FSH) were both significantly higher in exposed workers but there was no significant difference in the level of testosterone in both groups. Exposed workers showed a statistically significant increase in the incidence of sexual problems (premature ejaculation, impotence, decreased libido). Periodic medical examination of workers and biological monitoring of blood lead are a necessity for the early detection of side effects or complications caused by exposure.
||antifertility effects; male workers; exposure tests; testosterone; endocrine effects; lead
||exposure evaluation; determination in blood; endocrine function tests; case-control study
||D - Periodical articles
|Country / State or Province||Egypt|
||Mines and quarries
|Broad subject area(s)
Occupational medicine, epidemiology
||Antifertility and prenatal effects
Lead and compounds
Genetic factors in reaction to exposures