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Document ID (ISN)101050
CIS number 03-195
ISSN - Serial title 1219-1221 - Central European Journal of Occupational and Environmental Medicine
Year 2002
Convention or series no.
Author(s) Ibrahim K.S., Ahmed S.B.
Title Male endocrine dysfunction in lead smelter workers
Bibliographic information 2002, Vol.8, No.1, p.31-38. 36 ref.
Abstract Evidence of the effect of occupational exposure to lead on the male endocrine function is controversial. This study evaluated the primary (testicular) and secondary (hypothalamo-pituitary-testicular) effects of exposure to lead in 69 workers employed for an average of 16 years and in 40 non-exposed workers. The mean blood lead concentration was 42.92▒4.89Ág/dL in the exposed workers and 29.5▒ 5.3Ág/dL in the control group. Concentrations of serum luteinizing hormone (LH) and follicle stimulating hormone (FSH) were both significantly higher in exposed workers but there was no significant difference in the level of testosterone in both groups. Exposed workers showed a statistically significant increase in the incidence of sexual problems (premature ejaculation, impotence, decreased libido). Periodic medical examination of workers and biological monitoring of blood lead are a necessity for the early detection of side effects or complications caused by exposure.
Descriptors (primary) antifertility effects; male workers; exposure tests; testosterone; endocrine effects; lead
Descriptors (secondary) exposure evaluation; determination in blood; endocrine function tests; case-control study
Document type D - Periodical articles
Country / State or ProvinceEgypt
Subject(s) Mines and quarries
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Antifertility and prenatal effects
Biological monitoring
Lead and compounds
Inorganic substances
Genetic factors in reaction to exposures