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CISDOC database

Document ID (ISN)101002
CIS number 03-63
ISBN(s) 92-4-153043-X
Year 2002
Convention or series no. CICAD No.43
Author(s)
Inter-Organization Programme for the Sound Management of Chemicals (IOMC)
Title Acrolein
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2002. iv, 46p. 248 ref.
Internet access http://www.who.int/ipcs/publications/cicad/en/cicad43.pdf [in English]
Abstract Conclusions of this criteria document: acrolein is a strong upper respiratory tract and eye irritant in humans, as well as a mild skin irritant. Other reported effects of acute accidental exposure include weakness, nausea, vomiting, diarrhoea, shortness of breath, bronchitis and pulmonary oedema, possibly leading to death. Animal experiments show acrolein to have high acute toxicity. There are indications of genotoxicity in vitro. There is inadequate evidence of carcinogenicity in animal studies. The overall evaluation of IARC is that acrolein is not classifiable as to its carcinogenicity to humans (Group 3). Detailed summaries in French and Spanish.
Descriptors (primary) IPCS; acrolein; toxicology
Descriptors (secondary) toxic effects; pulmonary oedema; irritants; ILO; UNEP; WHO; IARC; dyspnoea; diarrhoea; vomiting; bronchitis; ecotoxicology; animal experiments; in vitro experiments; criteria document; literature survey
Document type B - Chemical safety information sheets
Country / State or ProvinceWHO
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aldehydes