ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)100994
CIS number 02-1932
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2002
Convention or series no.
Author(s) Goodno L.E., Stave G.M.
Title Primary and secondary allergies to laboratory animals
Bibliographic information Dec. 2002, Vol.44, No.12, p.1143-1152. Illus. 30 ref.
Abstract Although laboratory animal allergy (LAA) is a significant occupational hazard among workers exposed to laboratory animals, few studies have evaluated long-term risks to workers. In this study, surveillance data from a ten-year LAA prevention programme were analysed to estimate incidence rates of primary and secondary LAA and to evaluate the effectiveness of the prevention programme in reducing the development of primary LAA. The ten-year incidence rates of primary and secondary LAA were 1.34 and 11 cases per 100 person-years, respectively. The annual incidence of primary LAA was reduced from 3.6% to 0% in the first five years and did not rise above 1.2% over the remaining years, whereas the incidence of secondary LAA was greater than 8% in most years. These findings suggest that programmes effective at preventing primary LAA may need to be evaluated for their effectiveness at protecting against further risk.
Descriptors (primary) experimental animals; pharmaceutical industry; handling of animals; allergies
Descriptors (secondary) questionnaire survey; programme evaluation; frequency rates; statistical evaluation; medical supervision; risk factors
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Biological hazards
Browse category(ies) Livestock rearing
Animal hazards
Allergies
Pharmaceutical industry