Document ID (ISN) | 100994 |
CIS number |
02-1932 |
ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
Year |
2002 |
Convention or series no. |
|
Author(s) |
Goodno L.E., Stave G.M. |
Title |
Primary and secondary allergies to laboratory animals |
Bibliographic information |
Dec. 2002, Vol.44, No.12, p.1143-1152. Illus. 30 ref. |
Abstract |
Although laboratory animal allergy (LAA) is a significant occupational hazard among workers exposed to laboratory animals, few studies have evaluated long-term risks to workers. In this study, surveillance data from a ten-year LAA prevention programme were analysed to estimate incidence rates of primary and secondary LAA and to evaluate the effectiveness of the prevention programme in reducing the development of primary LAA. The ten-year incidence rates of primary and secondary LAA were 1.34 and 11 cases per 100 person-years, respectively. The annual incidence of primary LAA was reduced from 3.6% to 0% in the first five years and did not rise above 1.2% over the remaining years, whereas the incidence of secondary LAA was greater than 8% in most years. These findings suggest that programmes effective at preventing primary LAA may need to be evaluated for their effectiveness at protecting against further risk. |
Descriptors (primary) |
experimental animals; pharmaceutical industry; handling of animals; allergies |
Descriptors (secondary) |
questionnaire survey; programme evaluation; frequency rates; statistical evaluation; medical supervision; risk factors |
Document type |
D - Periodical articles |
Country / State or Province | USA |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
Biological hazards
|
Browse category(ies) |
Livestock rearing Animal hazards Allergies Pharmaceutical industry
|